Gene interactions and pathways from curated databases and text-mining

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CASP8 — ME2

Text-mined interactions from Literome

Zhang et al., Biosci Biotechnol Biochem 2008 (Leukemia) : Me(2)S ( 3 ) and Me(2)S ( 4 ) significantly induced DNA fragmentation and caspase-3 activation
Zhang et al., Biosci Biotechnol Biochem 2009 : Me(2)S ( 4 ) combined with beta-carotene and assisted by UVA significantly inhibited the cell viability, and enhanced the caspase-3 activity which was completely inhibited by N-acety-L-cysteine
Li et al., Neurol Res 2011 (Brain Ischemia) : 2ME2 may decrease the HIF-1-alpha expression, up-regulate the survivin expression, inhibit the expression of caspase-3 , and finally reduce apoptosis after GI