Gene interactions and pathways from curated databases and text-mining

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CASP8 — MEPE

Text-mined interactions from Literome

Goswami et al., J Neurosci Res 2000 : In summary, both the receptor mediated lowering of cAMP levels and the hydrolysis of 4,5-polyphosphoinositides have no direct effect on caspase-3 activity or apoptosis but do exacerbate the activation of caspase-3-like activity and subsequent cell death by apoptosis induced by inhibitors of 3-polyphosphoinositide synthesis
Gole et al., Comp Biochem Physiol C 1987 : The stimulation of influx of 45Ca2+ by 10 ( -3 ) M ACh was non-additive with the stimulation caused by caffeine, and 7 mM caffeine reduced the influx caused by 10 ( -3 ) M ACh
Itoh et al., J Physiol 1983 : In the presence of 3 X 10 ( -6 ) M-acetylcholine (ACh) , the efflux of 45Ca into Ca-free ( EGTA ) solution was accelerated and with the addition of 10 ( -5 ) M-NG plus 3 X 10 ( -6 ) M-ACh, this efflux was even further enhanced. ( ABSTRACT TRUNCATED AT 400 WORDS )