Gene interactions and pathways from curated databases and text-mining

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CASP8 — SRC

Text-mined interactions from Literome

Cursi et al., EMBO J 2006 (Colonic Neoplasms) : Src activation triggers Caspase-8 phosphorylation on Tyr380 and impairs Fas induced apoptosis ... Remarkably, Src activation upon EGF-receptor stimulation triggers endogenous Caspase-8 phosphorylation and prevents Fas induced apoptosis
Delivoria-Papadopoulos et al., Neurosci Lett 2012 (Anoxia) : Src kinase inhibitor also prevented the hypoxia induced increased activation of caspase-3 , a consequence of caspase-9 activation