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CASP8 — WDR61

Text-mined interactions from Literome

Ma et al., Curr Eye Res 2001 : PAF increases RCE and HCE apoptosis caused by UV irradiation by stimulating PLA(2), producing an early release of cytocrome c from mitochondria and activating caspase-3 by a receptor mediated mechanism
Hostettler et al., Glia 2002 (Inflammation...) : Immunocytochemistry demonstrated that PAF at all concentrations caused activation of caspase-3 at 24, 48, and 72 h after treatment in both cell types
Heon Seo et al., Cancer Res 2006 (Melanoma, Experimental) : Furthermore, PAF inhibited etoposide induced increases in caspase-3 , caspase-8, and caspase-9 activities, as well as cell death
Ryan et al., J Neurochem 2007 : Using PAFR-/- and congenic wild-type mice, we show that PAF triggers caspase-3/7 activity and neuronal death in PAFR-/- but not PAFR+/+ cerebellar granule neurons
Ryan et al., J Lipid Res 2008 : C16-PAF activates caspase-7 , whereas C18-PAF triggers caspase independent death in PAF receptor-deficient neurons
Zhao et al., Int J Cardiol 2010 (MAP Kinase Signaling System) : Second, we found that activity of p38-MAPK ( mitogen activated protein kinase ) and caspase-3 was elevated in the cells treated with PAF, without altering activity of ERK and JNK, and that PAF induced enhancement of caspase-3 activity was attenuated by application of either BAPTA/AM or SB203580 ( p38 inhibitor )