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FOXO1 — WNT1
Text-mined interactions from Literome
Wang et al., Clin Cancer Res 2009
(Endometrial Neoplasms) :
Progesterone induction of DKK1 and
FOXO1 results in inhibition of
Wnt signaling in the human endometrium
Manolopoulos et al., Mol Psychiatry 2010
(Alzheimer Disease...) :
Wnt inhibition may also
result in a sustained activation of
FoxO proteins with induction of apoptosis and neuronal loss, thereby completing a vicious circle from oxidative stress, InsRes and hyperglycaemia back to the formation of ROS and consecutive neurodegeneration
Chong et al., Curr Neurovasc Res 2011
(Diabetes Mellitus, Experimental...) :
EPO relies upon novel signaling of
Wnt1 that
requires Akt1,
FoxO3a , GSK-3ß, and ß-catenin to foster vascular integrity during experimental diabetes
Dieudonné et al., J Bone Miner Res 2012
(Bone Neoplasms...) :
Doxorubicin modulated Foxo3a binding on syndecan-2 gene promoter and induced
Foxo dependent inhibition of
Wnt/TCF activity