Gene interactions and pathways from curated databases and text-mining

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DST — IL18

Text-mined interactions from Literome

Novick et al., Cytokine 2001 (Sepsis) : We conclude that IL-18BPa considerably inhibits circulating IL-18 in sepsis
Marotte et al., Arthritis Rheum 2010 (Arthritis, Rheumatoid...) : Evaluation of signaling pathways suggested that TNFalpha induced IL-18 production through the ERK-1/2, protein kinase Cdelta (PKCdelta), and Src pathways, whereas IL-18BPa synthesis was mediated through the NFkappaB, PKC, Src, and JNK pathways