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SOCS2 — STAT3
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Shen et al., FEBS Lett 2000
:
Injection of IL-10 into mice activated
STAT3 but not STAT1 tyrosine phosphorylation and
induced suppressor of cytokine signal 2 (SOCS2) , SOCS3, and cytokine-inducible SH2 protein (CIS) mRNA expression in the liver
Sen et al., Clin Cancer Res 2012
(Carcinoma, Squamous Cell...) :
STAT5A mediated
SOCS2 expression
regulates Jak2 and
STAT3 activity following c-Src inhibition in head and neck squamous carcinoma ...
SOCS2 inhibits Janus kinase 2 (Jak2) activity and
Jak2-STAT3 binding ...
SOCS2 expression is
necessary for
STAT3 inhibition by c-Src inhibitors