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Fukuzono et al., Arch Biochem Biophys 2010
:
G-CSF mediated STAT3 phosphorylation and inhibition of TLR agonist induced cytokine production were prevented by pretreatment of cells with AG-490 ( JAK2 inhibitor )
Tel et al., Cancer Immunol Immunother 2012
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Furthermore, oxaliplatin decreased TLR induced STAT1 and STAT3 expression, and NF-?B mediated responses
Ochi et al., J Clin Invest 2012
(Carcinoma, Pancreatic Ductal...) :
Furthermore, TLR7 ligation induced STAT3 activation and interfaced with Notch as well as canonical NF-?B and MAP kinase pathways, but downregulated expression of Notch target genes