◀ Back to WNT4
SOX13 — WNT4
Text-mined interactions from Literome
Kormish et al., Dev Dyn 2010
(Neoplasms) :
In some contexts,
Wnt signaling also
regulates SOX expression resulting in feedback regulatory loops that fine-tune cellular responses to beta-catenin/TCF activity
Marfil et al., J Biol Chem 2010
:
We show that Hhex is able to block the
SOX13 dependent repression of
Wnt/TCF activity by displacing SOX13 from the SOX13 x TCF1 complex ... We conclude that the interaction between Hhex and
SOX13 may
contribute to control
Wnt/TCF signaling in the early embryo
Wang et al., J Biol Chem 2013
(Breast Neoplasms...) :
Consistently,
SOX9 overexpression in BCa cell lines and transgenic SOX9 expression in breast epithelium
caused increased LRP6 and TCF4 expression and
Wnt/ß-catenin activation