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ICAM1 — PTX4

Text-mined interactions from Literome

Gu et al., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2006 : To investigate the effects of pentoxifylline ( PTX ) on the expression of intercellular adhesion molecule-1 ( ICAM-1 ) of rat cardiac myocytes after lipopolysaccharide (LPS) challenge in vitro, and to evaluate the protective effect of PTX on cardiac myocytes and its mechanism
Sun et al., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2007 : To investigate the inhibitory effects of anisodamine ( 654-2 ) and pentoxifylline ( PTX ) on the expression of lipopolysaccharide (LPS) induced intercellular adhesion molecule-1 ( ICAM-1 ) in rat cardiac muscle in vivo
Parhar et al., Mediators Inflamm 1993 : Finally, the effect of PTX on the expression of adhesion molecules ( LFA-1, Mac-1 and ICAM-1 ), and cytokine ( IL-1alpha, IL-2, TNF-alpha, IL-6 and IFN-gamma ) production and their surface receptor expression in response to LPS activation was investigated
Richard et al., Brain Pathol 2011 (Encephalomyelitis, Autoimmune, Experimental) : In a series of experiments using DNA microarrays, knockout mice and neutralizing antibodies, we found that PTX acts indirectly on the endothelium in part through IL6, which is essential for the post-transcriptional upregulation of intercellular adhesion molecule 1 ( ICAM1 ) in response to PTX but not to LPS
Bruynzeel et al., J Invest Dermatol 1995 : The interferon-gamma induced ICAM-1 expression was not blocked by PTX
Jewett et al., J Clin Immunol 1994 : Also, PTX inhibited IL-2 triggered upregulation of the expression of CD69, CD25, ICAM-1 , and p75TNF-R on the cell surface ... Also, PTX inhibited IL-2 triggered upregulation of the expression of CD69, CD25, ICAM-1 , and p75TNF-R on the cell surface
Mándi et al., Res Exp Med (Berl) 1995 (Sepsis) : Cytofluorometric analysis revealed that the expression of ICAM-1 on stimulated mononuclear cells was inhibited by PTX
Neuner et al., Immunology 1997 : Since pentoxifylline ( PTX ) was recently recognized as a substance with antiinflammatory capacities, we studied the in vivo and in vitro effect of PTX on the expression of the intercellular adhesion molecule-1 ( ICAM-1 ) on human monocytes ... The inhibitory effect of PTX on ICAM-1 expression in monocytes could be reversed by the addition of exogenous tumour necrosis factor-alpha ( TNF-alpha ; 200 U/ml ) suggesting that ICAM-1 down-regulation is mediated secondary to TNF-alpha suppression by PTX ... The observed suppressive in vivo and in vitro effects of PTX on ICAM-1 expression in monocytes may contribute to the recently described antiinflammatory effects of PTX, e.g. in sepsis or allergic contact dermatitis