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CASP4 — TLR9

Text-mined interactions from Literome

Mariathasan et al., Nature 2004 (Inflammation...) : Unexpectedly, Ipaf-deficient macrophages activated caspase-1 in response to TLR plus ATP stimulation but not S. typhimurium
Hewinson et al., J Immunol 2008 (Ion Channel Gating) : P2X(7) receptors ( P2X(7)Rs ) are ATP gated ion channels that trigger caspase-1 activation in the presence of TLR ligands
Netea et al., Blood 2009 (Inflammation) : Controversy has arisen whether Toll-like receptor ( TLR ) ligands alone can activate caspase-1 for release of interleukin-1beta (IL-1beta)
Hurst et al., Immunobiology 2009 (Antiphospholipid Syndrome) : Determination of expression-levels using real-time RT-PCR showed significantly augmented TLR dependent IL-1beta and caspase-1 expression