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CXCL10 — IL10

Text-mined interactions from Literome

Albanesi et al., J Immunol 2000 (Calcium Signaling...) : IL-4, but not IL-10 or IL-17, significantly up-regulated IFN-gamma- or TNF-alpha induced IP-10, Mig, and I-TAC mRNA accumulation in keratinocytes and increased the levels of IP-10 and Mig in keratinocyte supernatants
Kasama et al., Cell Immunol 2002 (Neovascularization, Pathologic) : In contrast, IL-10 , recognized as an anti-inflammatory cytokine, significantly inhibited IP-10 secretion by co-cultures
Cheeran et al., J Virol 2003 (Cytomegalovirus Infections) : CXCL10 production from cytomegalovirus stimulated microglia is regulated by both human and viral interleukin-10 ... The IL-10 mediated inhibition of CXCL10 production was associated with decreased CMV induced NF-kappa B activation but not decreased p38 MAP kinase phosphorylation
Wright et al., J Clin Immunol 2003 (Osteomyelitis...) : We investigated the potential down-regulators of chemokine secretion IL-4, IL-10 , IL-13, dexamethasone, and PGE2, IL-10 and IL-13 down-regulate M. tuberculosis induced IL-8, IP-10 , RANTES, and MCP-1 secretion from MG-63 cells by between 48 and 94 % ( P < 0.05 ) but do not inhibit chemokine gene transcription
Marques et al., Glia 2004 (Encephalitis, Herpes Simplex) : Results from these studies demonstrated a consistent IL-10 mediated suppression of TNF-alpha ( 60 % +/- 2 % ), IL-1beta ( 68 % +/- 3 % ), CCL5 ( 62 +/- 4 % ), but not CXCL10 production by HSV-1 infected microglial cells
Wright et al., Microbes Infect 2004 : IL-10 and IL-13 reduced S. aureus induced osteoblast C-X-C chemokine secretion, whereas IL-4 decreased CXCL8 secretion 2.5-fold and increased CXCL10 secretion 3-fold ( all P < 0.05 ) ... IL-10 and IL-13 reduced S. aureus induced osteoblast C-X-C chemokine secretion, whereas IL-4 decreased CXCL8 secretion 2.5-fold and increased CXCL10 secretion 3-fold ( all P < 0.05 )
Imakawa et al., Am J Reprod Immunol 2005 : Endometrial chemokine IP-10 could regulate IL-10 production by resident and possibly migrated cells expressing CD11b, probably natural killer cells, and these changes may result in immune environments of the uterus suitable for conceptus implantation in ruminants
Giacomini et al., Infect Immun 2006 : On the other hand, IL-10 impaired CXCL10 production in sigE mutant infected DC and, indeed, its neutralization restored CXCL10 secretion ... Thus, our findings suggest that the sigE mutant induced secretion of IL-10 inhibits CXCL10 expression and, in turn, the recruitment of activated-effector cells involved in the formation of granulomas
Rossato et al., Eur J Immunol 2007 : We also show that IL-10 induced transcriptional repression of TNF-alpha and CXCL8 genes consists of two distinct phases : an early one, occurring rapidly and in a protein synthesis independent manner, followed by a second phase, more delayed and dependent on protein synthesis
Vasquez et al., Infect Immun 2008 (Leishmaniasis) : We found that CXCL10 induced IL-12 p40 production but reduced IL-10 production in uninfected DCs
Tamassia et al., Int Immunol 2008 (Sepsis...) : Consistent with the presence of a fully functional IL-10R, modulation of LPS induced CXCL8 , CCL4, tumour necrosis factor-alpha and IL-1ra gene expression was also rapidly induced by IL-10 in septic, but not normal, neutrophils
Hosokawa et al., J Periodontal Res 2009 (Periodontitis) : However, interleukin-4 and interleukin-13 inhibited CXCL10 production by interferon-gamma stimulated or tumor necrosis factor-alpha-stimulated-human gingival fibroblasts ... On the other hand, interleukin-17A and interleukin-22 enhanced CXCL10 production by human gingival fibroblasts treated with interferon-gamma and inhibited CXCL10 production by tumor necrosis factor-alpha stimulated human gingival fibroblasts
Tousi et al., Neurosci Lett 2012 (Parkinson Disease) : a-Synuclein potentiates interleukin-1ß induced CXCL10 expression in human A172 astrocytoma cells
Sabado et al., Journal of visualized experiments : JoVE 2013 : Our previous study established that Poly-ICLC is the most potent individual maturation stimulus for human DCs as assessed by an upregulation of CD83 and CD86, induction of interleukin-12 (IL-12), tumor necrosis factor (TNF), interferon gamma induced protein 10 (IP-10) , interleukmin 1 (IL-1), and type I interferons ( IFN ), and minimal interleukin 10 (IL-10) production
Cassatella et al., Eur J Immunol 1997 : Finally, we found that interleukin-10 , a known inhibitor of chemokine production in PMN, moderately suppressed the extracellular production of IP-10 in neutrophils stimulated with IFN-gamma plus either LPS or TNF-alpha
Tebo et al., Blood 1998 : Interleukin-10 suppresses IP-10 gene transcription by inhibiting the production of class I interferon ... Interestingly, the ability of IL-10 to inhibit expression of IP-10 was dependent on the inducing stimulus ; IL-10 did not suppress interferon gamma (IFNgamma)- or IFNbeta stimulated IP-10 transcription or mRNA accumulation ... Finally, the IL-10 mediated suppression of LPS stimulated IP-10 production could be rescued by cotreatment with IFNbeta