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HDAC1 — SLC22A3

Text-mined interactions from Literome

Lei et al., Int J Biochem Cell Biol 2010 : Expression of a dominant negative mutant of HDAC1 but not HDAC2 or downregulation of HDAC1 but not HDAC2 by RNAi suppressed TGF-beta1 induced EMT ... Conclusions : our results demonstrate that HDAC1 is required for TGF-beta1 induced EMT and cell migration in hepatocytes ... The data also suggest that the repression of transcription of ZO-1 and E-cadherin by HDAC1 may be involved in TGF-beta1 induced EMT
Giudice et al., PloS one 2013 (Carcinoma, Squamous Cell...) : Paradoxically, inhibition of HDAC also induced epithelial-mesenchymal transition (EMT) in HNSCC cells, accumulation of BMI-1, an oncogene associated with tumor aggressiveness, and expression of the vimentin mesenchymal marker