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KISS1 — LEP
Text-mined interactions from Literome
Smith et al., J Neuroendocrinol 2006
:
First, we examined whether
leptin regulates the expression of
Kiss1 by comparing levels of KiSS-1 mRNA in the arcuate nucleus among groups of mice having different circulating levels of leptin : ( i ) wild-type (WT); (ii) leptin-deficient ob/ob ; and ( iii ) ob/ob mice treated with leptin
Luque et al., Endocrinology 2007
(Obesity) :
Moreover,
leptin , but not insulin or IGF-I,
stimulated KiSS-1 mRNA expression in the mouse hypothalamic cell line N6
Morelli et al., J Sex Med 2008
:
In addition,
leptin ( 1 nM, 24 hours ), an adipocyte derived hormone acting on the reproductive axis, significantly
increased KiSS-1/GPR54 expression in FNC-B4