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CFL1 — EGFR

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: Complex of 168 proteins Blagoev et al., Nat Biotechnol 2003
• IRef Intact Interaction: Complex of 228 proteins (association, pull down) Blagoev et al., Nat Biotechnol 2003
• IRef Intact Interaction: EGFR — CFL1 (physical association, ubiquitin reconstruction) Deribe et al., Science signaling 2009

Text-mined interactions from Literome

Marcoux et al., Cell Signal 2005 : Instead, we found that EGFR activity is required for integrin induced phosphorylation of cofilin
Nishimura et al., Histochem Cell Biol 2006 (Breast Neoplasms) : We further analyzed the effect of S3A cofilin mutant on EGFR trafficking, and found an efficient delivery of Texas red-EGF into late endosomes/lysosomes at 15-30 min after internalization
Karlsson et al., Mol Endocrinol 2010 : LHR dependent Rho inactivation and subsequent activation of cofilin does not involve ERK, epidermal growth factor receptor , or phosphatidylinositol 3-kinase pathways downstream of PKA