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EDNRA — IGF1

Text-mined interactions from Literome

Yano et al., Endocrinology 1999 : While IGF-I stimulated membrane translocation of PKC-eta , -epsilon, and -zeta and regulated the cytosolic levels of PKC-betaI, it had no such effect on PKC-alpha and -lambda ... These results indicated that PKC-betaI, -eta , -epsilon, and -zeta may play an essential role ( s ) in IGF-I regulation of VSMC migration, DNA synthesis and gene expression, and that these PKC isoforms may either act independently of the PI3 kinase pathway or act further downstream of PKB/Akt in the IGF signaling network
Zhang et al., Brain Res Dev Brain Res 2003 : Our finding of IGF-I induced down-regulation of 14-3-3 eta expression in Purkinje cell at a time when IGF-I promotes granule cell survival leads us to speculate that down-regulation of 14-3-3 eta may : ( a ) serve a negative feedback role to modulate Purkinje cell survival, i.e. limit Purkinje cell number, and/or ( b ) function as part of a distinct signaling mechanism, perhaps one that augments the capacity of Purkinje cells to promote granule cell survival
Kwok et al., J Cell Biochem 2005 : We therefore carried out the present study to determine the effect of IGF-1 on the binding of ET-1 to, and ET type A receptor (ETAR) expression and ET-1 induced 3H-thymidine incorporation in, vascular SMCs