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MMP28 — RAC1
Text-mined interactions from Literome
Zhuge et al., J Biol Chem 2001
(Carcinoma, Squamous Cell...) :
The
Rac1 dependent MMP-2 activation occurred in a cell associated fashion and
required MMP activities
Stallings-Mann et al., Sci Transl Med 2012
(Adenocarcinoma...) :
We show that expression of mouse Rac1b in lung epithelial cells of transgenic mice stimulated EMT and spontaneous tumor development and that activation of EMT by
MMP induced expression of
Rac1b gave rise to lung adenocarcinoma in the transgenic mice through bypassing oncogene induced senescence
Serratì et al., Arthritis Rheum 2013
(Scleroderma, Systemic) :
Motility increase required
Rac1 activation and RhoA inhibition and was
inhibited by an
MMP inhibitor