UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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DROSHA — FUS

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

MIPS CORUM Large Drosha complex: Large Drosha complex complex (DDX1-DDX17-DDX3X-DDX5-DGCR8-DHX15-EWSR1-FUS-HNRNPH1-HNRNPM-HNRNPU-HNRNPUL1-HNRNPDL-ILF2-ILF3-RALY-DROSHA-SRPK1-TAF15-TARDBP) Gregory et al., Nature 2004
IRef Corum Interaction: Complex of 41 proteins (association, anti tag coimmunoprecipitation) Gregory et al., Nature 2004
IRef Intact Interaction: FUS — DROSHA (physical association, anti tag coimmunoprecipitation) Morlando et al., EMBO J 2012 *
IRef Intact Interaction: FUS — DROSHA (physical association, pull down) Morlando et al., EMBO J 2012 *