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ANGPT2 — MMP15

Text-mined interactions from Literome

Etoh et al., Cancer Res 2001 (Neovascularization, Pathologic...) : MMP-1, MMP-9 , and urokinase-type plasminogen activator in ECs were strongly up-regulated by Ang-2 in the presence of VEGF in vitro
Nazari et al., J Med Invest 2007 (MAP Kinase Signaling System) : We next tested the effect of broad-spectrum matrix metalloproteinase ( MMP ) inhibitor ( GM6001 ) on Ang II-inhibition of insulin signaling pathway
Zack et al., Atherosclerosis 2011 (Aortic Aneurysm, Abdominal...) : Ang II induction of cyclooxygenase-2, interleukin-6, matrix metalloproteinase (MMP)-2 , MMP-13 and MMP-14 was reduced significantly in GX DKO mice compared to apoE ( -/- ) mice
Martinez-Lemus et al., Am J Physiol Heart Circ Physiol 2011 (Disease Models, Animal...) : Inhibition of MMP activation ( with GM-6001 ) or ROS production ( with apocynin or tempol ) prevented the NE + ANG II-induced inward remodeling