Lezin et al., AIDS Res Hum Retroviruses 2000
(HTLV-I Infections...) :
TIMP-3 , a regulator of MMP activity and cell survival, was detected with a significantly higher frequency in the TSP/HAM group and paralleled the increased levels of MMP-9 and neopterin, a sensitive indicator of cellular immune activation
Jin et al., Int J Cancer 2010
(Neoplasm Metastasis...) :
Gene array analysis revealed that blocking Snail expression suppressed the activity of matrix metalloproteinases ( MMPs ) and upregulated TIMP3 , an MMP inhibitor
Lemke et al., Cell Tissue Res 2010
(Arthritis) :
TIMP-3 ( but not TIMP-1 and -2 or a broad spectrum MMP inhibitor ) inhibited IL-1 dependent GAG loss