Sedlik et al., J Immunol 2003
:
Importantly, Syk was also required for the induction of DC maturation and IL-12 production after FcR engagement, but not after engagement of other surface receptors, such as TNFR or Toll-like receptors
Skrzypek et al., Microbes Infect 2009
:
Indeed, specific Syk inhibition significantly suppressed the production of IL-12 , IL-6, and TNF-alpha