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HSPB1 — PTGS2
Text-mined interactions from Literome
Lasa et al., Mol Cell Biol 2000
(MAP Kinase Signaling System) :
The MAPKAPK-2 substrate hsp27 may be involved in stabilization, as
beta-globin-Cox-2 transcripts were partially
stabilized by phosphomimetic mutant forms of
hsp27
Liu et al., Cell Immunol 2010
(Inflammation) :
In the present study, both overexpression and RNA interference experiments indicated that
HSP27 increased LPS induced expression of iNOS and
COX-2 and release of NO/PGE2 through enhancing NF-kappaB but not MAPK activation ... The
effects of
HSP27 on LPS induced
iNOS/COX-2 expression and relative signaling cascade were closely related with the phosphorylation of HSP27