UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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IL12RB1 — MTOR

Pathways - manually collected, often from reviews:

NCI Pathway Database IL12-mediated signaling events: IL12/IL12R/TYK2/JAK2 complex (IL12A-IL12B-IL12RB1-IL12RB2-TYK2-JAK2) → mTOR (MTOR) (modification, activates) Kusaba et al., J Biol Chem 2005
Evidence: mutant phenotype, assay, physical interaction