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CDH10 — HDAC1
Text-mined interactions from Literome
Yamaguchi et al., Cancer Sci 2010
(Gallbladder Neoplasms) :
In TGBC2TKB cells, the expression of EZH2 and
HDAC1/2 were decreased by SAHA treatment, and p16(INK4a),
E-cadherin , and p21were simultaneously
activated ; however, no such findings were obtained in HGECs, suggesting that the effect of SAHA depends on the EZH2 mediated tumor suppressor loss
Huang et al., Mol Pharmacol 2011
:
This finding, together with the
HDAC inhibitor
induced up-regulation of KLF4 and
E-cadherin , suggests that HDAC inhibitors could activate the expression of these genes through changes in histone methylation status
Iordache et al., International journal of molecular sciences 2012
:
RT-PCR assay showed that
HDAC inhibitors
down-regulated the expression of endothelial genes such as
VE-cadherin , CD133, CXCR4 and Tie-2