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AKT3 — E2F8
Text-mined interactions from Literome
Gille et al., J Biol Chem 1999
:
Activated PI 3-kinase
induces cyclin D(1) transcription and
E2F activity, at least in part mediated by the serine/threonine kinase
Akt/PKB , and to a lesser extent the Rho family GTPase Rac
Chaussepied et al., Mol Cell 2004
:
Transcriptional
regulation of
AKT activation by
E2F ... We identify the adaptor protein Grb2 associated binder 2 (Gab2) as a direct E2F target gene and an essential effector of
E2F dependent
AKT activation
Yin et al., Prostate 2009
(Prostatic Neoplasms) :
In prostate cancer C/EBPalpha promotes cell growth by the loss of interactions with CDK2, CDK4, and
E2F and by
activation of
AKT
Dar et al., J Biol Chem 2011
(Melanoma...) :
The proliferative capacity of melanoma cells was suppressed by miR-205 and mediated by
E2F regulated
AKT phosphorylation