◀ Back to PAK1
CCNC — PAK1
Text-mined interactions from Literome
Messerli et al., Phytother Res 2009
(Neoplasms, Experimental...) :
Artepillin C (ARC) in Brazilian green propolis selectively
blocks oncogenic
PAK1 signaling and suppresses the growth of NF tumors in mice ... Also it was demonstrated that ARC suppresses angiogenesis, suggesting the possibility that
ARC also
blocks oncogenic
PAK1 signaling ... Here it is shown for the first time that both
ARC and green propolis extract ( GPE ) indeed
block the
PAK1 signaling selectively, without affecting another kinase known as AKT
Crespin et al., Blood Coagul Fibrinolysis 2009
:
Inhibition of Cdc42 and Rac1 by toxin B from Clostridium difficile, that suppresses
PAK1/2 activation
induced by
TRAP and collagen or by A23187 in the presence of calpeptin, decreases polymerization of actin, lamellipodia and filopodia formation and interferes with the shedding of microvesicles