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GTS — PTX4

Text-mined interactions from Literome

Tsai et al., Neuroscience 2009 (Hyperalgesia...) : Ultra-low dose naloxone plus morphine significantly inhibited the effect of PTX on P-p38 MAPK expression in the spinal cord, while the p38 MAPK inhibitor SB203580 attenuated the PTX induced mechanical allodynia, thermal hyperalgesia, increase in spinal cerebrospinal fluid excitatory amino acids, and downregulation of GTs
Wong et al., Brain Res Bull 2009 (Hyperalgesia) : Intrathecal morphine failed to produce antinociceptive effects in PTX treated rats, and d-AP5 coinfusion prevented the PTX induced reduction in the antinociceptive effect and associated downregulation of the GTs