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CXCL2 — TLR2

Text-mined interactions from Literome

Hung et al., Nephrol Dial Transplant 2006 : The LMPS enhanced the secretion of CCL2/MCP-1 and CXCL8/interleukin-8 (CXCL8/IL-8) in TLR-defective human embryonic kidney (HEK) 293 cells only when transfected with a TLR2 expressing plasmid
Bsibsi et al., Glia 2007 : Moreover, the CD14 triggered TLR2 mediated response in astrocytes lead to the production of CXCL8 , IL-6, and IL12p40, whereas typical TLR induced pro-inflammatory cytokines, like TNF-alpha and IL-1beta, were not produced at detectable levels
Méndez-Samperio et al., Arch Med Res 2008 : Moreover, it is important to note that the levels of CXCL8 secretion and mRNA were markedly ( 94 % ) reduced by functional blocking of both TLR2 and TLR4
Wang et al., Blood 2008 : We and others have reported that Toll-like receptor ( TLR ) proteins are present on human neutrophils and that granulocyte-macrophage colony stimulating factor ( GM-CSF ) treatment enhances IL-8 ( CXCL8 ) secretion in response to stimulation with TLR ligands
Lee et al., J Clin Immunol 2009 : These results indicate that TLR2-ROS signaling plays a crucial role in the 30-kDa Ag-mediated expression of CXCL8 and CCL2 in human monocytes
Lee et al., Cell Microbiol 2009 : In addition, TLR2 , Dectin-1 and, to an extent, TLR4 are essential for the MU-mediated expression of CXCL8 , CCL2 and LL-37 in keratinocytes ... In addition, TLR2 , Dectin-1 and, to an extent, TLR4 are essential for the MU-mediated expression of CXCL8 , CCL2 and LL-37 in keratinocytes
Farges et al., Immunobiology 2011 : We found that odontoblasts produce the pro-inflammatory cytokines interleukin (IL)-6 and CXCL8 , as well as the immunosuppressive cytokine IL-10 in response to TLR2 agonists
Sharma et al., J Leukoc Biol 2013 : Our findings reveal a previously unrecognized role for S1P in regulating TLR induced CXCL8 secretion from human T cells