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AKT3 — CCR7
Text-mined interactions from Literome
Riol-Blanco et al., J Immunol 2005
(MAP Kinase Signaling System) :
CCR7 induced activation of
PI3K/Akt ; however, these enzymes did not regulate either chemotaxis or the speed of DCs
Liu et al., Mol Immunol 2007
:
Further studies show that the triptolide mediated inhibitory effects of LPS induced activation of phosphatidylinositol-3 kinase
(PI3-K)/Akt and nuclear NF-kappaB activation are
involved in down-regulation of COX-2 and
CCR7 expression resulting in impaired migration to secondary lymphoid organs of DC
Xu et al., PloS one 2011
(Carcinoma, Non-Small-Cell Lung...) :
The
CCL21/CCR7 interaction significantly
enhanced phosphorylation of extracellular signal regulated kinase ( P-ERK ) but not
Akt , as measured by Western blot