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CCR2 — MAPK3
Pathways - manually collected, often from reviews:
-
OpenBEL Selventa BEL large corpus:
MAPK3
→
CCR2
(increases)
Nanki et al., J Immunol 2001*
Evidence: Treatment of fibroblast-like synoviocyte (FLS) cultures with RS-504393, a CCR-2 antagonist significantly inhibited the CCL-2 induced ERK1 activation, indicating that CCL-2 induced ERK1 activation was mediated by CCR-2.
Text-mined interactions from Literome
Hirata Terra et al., Anal Biochem 2004
:
MCP-1 induced phosphorylation of p44/42
MAPK is
dependent upon the expression of
CCR2B
Choi et al., Fitoterapia 2011
(Leukemia, Monocytic, Acute) :
Herein, we investigated the effects of Rh1 on the expression of MCP-1 and
CCR2 ,
activation of
MAPK signaling, and chemotaxis of monocytes