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NEUROG3 — NOTCH2
Text-mined interactions from Literome
Ahnfelt-Rønne et al., BMC developmental biology 2007
:
Notably, activated Notch also prevents Ngn3 mediated induction of a number of downstream targets including NeuroD, Hes6-1, and MyT1 suggesting that
Notch may act to
inhibit both
Ngn3 gene expression and protein function
Dror et al., Diabetologia 2007
:
Inhibiting
Notch signalling with N- [ N- ( 3,5-difluorophenacetyl-L-alanyl ) ] -S-phenylglycine t-butyl ester ( DAPT )
increased Ngn3 mRNA expression and protein levels in adult islets
Serafimidis et al., Stem Cells 2008
:
Induction of
Ngn3 expression
results in regulation of the Wnt, integrin,
Notch , and transforming growth factor beta signaling pathways and changes in biological processes affecting cell motility, adhesion, the cytoskeleton, the extracellular matrix, and gene expression
Golson et al., Mech Dev 2009
:
Ngn3 expression is
repressed by active
Notch signaling
Qu et al., Dev Biol 2013
:
Notch mediated post-translational control of
Ngn3 protein stability regulates pancreatic patterning and cell fate commitment