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STAT1 — VEGFA

Pathways - manually collected, often from reviews:

• KEGG Pathways in cancer: STAT1 → FIGF/PGF/VEGFA/VEGFB/VEGFC (gene expression, expression)
  
• KEGG Pancreatic cancer: STAT1 → FIGF/PGF/VEGFA/VEGFB/VEGFC (gene expression, expression)
  

Text-mined interactions from Literome

Bartoli et al., J Biol Chem 2000 : Here, we show that VEGF induces tyrosine phosphorylation and nuclear translocation of STAT1 and STAT6 ... However, upon VEGF stimulation, STAT1 associates with the VEGFR2 in a tyrosine kinase dependent manner, indicating that VEGF induced STAT1 activation is mediated primarily by VEGFR2
Weis et al., Mol Biol Cell 2009 : Whereas VEGFA release from macrophages was signal transducer and activator of transcription ( STAT ) 1-dependent, vascular endothelial growth factor itself triggered STAT1/STAT3 heterodimer formation, which bound to and activated the HO-1 promoter
Albasanz-Puig et al., Biochem Biophys Res Commun 2012 : Opposing roles of STAT-1 and STAT-3 in regulating vascular endothelial growth factor expression in vascular smooth muscle cells ... We further show that the mechanism by which STAT-1 and STAT-3 regulates VEGF expression is through modulation of Hypoxia Inducible Factor-1a (HIF-1a) ... These results provide evidence that activated STAT-1 and STAT-3 regulate VEGF expression indirectly, by modulating HIF-1a activity