Gene interactions and pathways from curated databases and text-mining

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RELA — TYK2

Text-mined interactions from Literome

Yang et al., J Biol Chem 2005 (Fibrosarcoma) : In the IFN signaling pathway leading to STAT activation, both JAK1 and TYK2 are essential, whereas NF-kappaB activation requires only TYK2
Li et al., Arterioscler Thromb Vasc Biol 2007 (Atherosclerosis...) : JAK1/TYK2 leads to STAT3 activation, Akt dependent NF-kappaB activation, and phosphorylation of extracellular signal regulated kinase 1/2 and mitogen activated kinase p38