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GATA6 — WNT2

Text-mined interactions from Literome

Zhang et al., Nat Genet 2008 : Together, these data demonstrate that Gata6 regulated Wnt signaling controls the balance between progenitor expansion and epithelial differentiation required for both lung development and regeneration
Zhong et al., PloS one 2011 (Carcinoma in Situ...) : GATA6 activates Wnt signaling in pancreatic cancer by negatively regulating the Wnt antagonist Dickkopf-1 ... Forced overexpression of GATA6 in cancer cell lines enhanced cell proliferation and colony formation in soft agar in vitro and growth in vivo, as well as increased Wnt signaling ... Forced overexpression of DKK1 antagonized the effects of GATA6 on Wnt signaling in pancreatic cancer cells