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HDAC2 — WNT2
Text-mined interactions from Literome
Sierra et al., Genes Dev 2006
:
We conclude that, in addition to regulating the stability of beta-cat, APC facilitates
CtBP mediated repression of
Wnt target genes in normal, but not in colorectal cancer cells
Debeb et al., Stem Cells 2012
(Breast Neoplasms...) :
Moreover, while
HDAC inhibitors upregulated ß-catenin expression and significantly
increased WNT reporter activity, a TCF4 dominant negative construct abolished HDAC-inhibitor induced expansion of CSCs
Aldiri et al., Development 2013
(Wnt Signaling Pathway) :
We also show that
Wnt/ß-catenin signaling acting through the receptor Frizzled 5, but independent of Sox2,
regulates expression of key
PRC2 subunits in the developing retina