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LGR4 — WNT2
Text-mined interactions from Literome
Glinka et al., EMBO Rep 2011
(Wnt Signaling Pathway) :
Gain- and loss-of-function experiments in mammalian cells and Xenopus embryos indicate that
LGR4 and LGR5
promote R-spondin mediated
Wnt/ß-catenin and Wnt/PCP signalling
Deng et al., J Cell Sci 2013
(Wnt Signaling Pathway) :
Using newly available genome sequences, we showed that norrin is a vertebrate ortholog for insect burs and pburs and stimulates
Wnt signaling
mediated by
LGR4 , but not by LGR5 and 6, in mammalian cells
Qian et al., Development 2013
(Wnt Signaling Pathway) :
Lgr4 mediated
Wnt/ß-catenin signaling in peritubular myoid cells is essential for spermatogenesis