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BRCA1 — CDK4

Pathways - manually collected, often from reviews:

• Reactome Reaction: BRCA1 → CDK4 (direct_complex) Masson et al., EMBO J 1999, Sehorn et al., Nature 2004, Oliver-Bonet et al., Mol Hum Reprod 2005, Thorslund et al., EMBO J 2007, Oliver-Bonet et al., Mol Hum Reprod 2007, Sheridan et al., Nucleic Acids Res 2008, Okorokov et al., PloS one 2010, Scully et al., Cell 1997, Barlow et al., EMBO J 1997, Golub et al., Nucleic Acids Res 1998

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: BRCA1 — CDK4 Wang et al., Oncogene 1997
• IRef Bind_translation Interaction: BRCA1 — CDK4 (affinity chromatography technology) Wang et al., Oncogene 1997
• IRef Biogrid Interaction: BRCA1 — CDK4 (direct interaction, enzymatic study) Miralem et al., Mol Cell Biol 2003*
• IRef Biogrid Interaction: BRCA1 — CDK4 (direct interaction, pull down) Wang et al., Oncogene 1997
• IRef Biogrid Interaction: BRCA1 — CDK4 (direct interaction, enzymatic study) Kehn et al., Oncogene 2007*
• IRef Hprd Interaction: BRCA1 — CDK4 (in vivo) Wang et al., Oncogene 1997
• IRef Hprd Interaction: BRCA1 — CDK4 (in vitro) Wang et al., Oncogene 1997
• IRef Ophid Interaction: BRCA1 — CDK4 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome