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MAPK1 — MYLIP
Text-mined interactions from Literome
Cheng et al., Neuron 2007
(MAP Kinase Signaling System) :
miR-132 is induced by photic entrainment cues via a
MAPK/CREB dependent mechanism, modulates clock-gene expression, and attenuates the entraining effects of light
Kim et al., J Biol Chem 2008
(Neoplasm Invasiveness) :
MicroRNA
miR-199a* regulates the MET proto-oncogene and the downstream
extracellular signal regulated kinase 2 ( ERK2 ) ... Interestingly,
extracellular signal regulated kinase 2 ( ERK2 ) was also
down-regulated by
miR-199a*
Akhtar et al., Arthritis Rheum 2010
(Osteoarthritis) :
NF-kappaB and
MAPK activation
down-regulated the expression of
miR-27b
Cannell et al., Proc Natl Acad Sci U S A 2010
(MAP Kinase Signaling System) :
p38
MAPK/MK2 mediated
induction of
miR-34c following DNA damage prevents Myc dependent DNA replication
Liu et al., PloS one 2011
(Neovascularization, Pathologic) :
AKT and extracellular regulated kinases
(ERK) 1/2 are
activated by
miR-21
Tan et al., FEBS Lett 2011
(Carcinoma, Hepatocellular...) :
Forced expression of
miR-198 decreased c-MET expression at both mRNA and protein levels and consequently diminished HGF
induced phosphorylation of p44/42
MAPK in HCC cells
Zhang et al., FEBS Lett 2012
(Diabetic Nephropathies...) :
We found that miR-451 negatively regulated the expression of Ywhaz through Ywhaz 3'UTR and that Ywhaz was required for the
miR-451 mediated downregulation of p38
MAPK signalling ... These findings suggest that the growth-inhibitory effect of miR-451 may be explained in part by
miR-451 induced suppression of Ywhaz and p38
MAPK signalling, providing evidence for the potential role of miR-451 in early DN
Liu et al., J Biol Chem 2011
:
The up-regulation of
rno-miR-31 in proliferative VSMCs was
inhibited by the inhibitor of mitogen activated protein kinase/extracellular regulated kinase (
MAPK/ERK )
Ciuffreda et al., J Mol Med (Berl) 2012
(Disease Models, Animal...) :
This appears to be a general regulatory mechanism and is mediated by multiple mechanisms, such as
MAPK dependent c-Jun and
miR-25 regulation
Sharma et al., EMBO Mol Med 2012
(Cardiomegaly...) :
Repression of
miR-142 by p300 and
MAPK is required for survival signalling via gp130 during adaptive hypertrophy
Jude et al., Am J Physiol Lung Cell Mol Physiol 2012
(Asthma...) :
TNF-a induced activation of p38
MAPK and NF-?B was
attenuated by
miR-140-3p mimic
Liang et al., Gastroenterology 2013
(Colorectal Neoplasms...) :
Ectopic expression of
miR-137 in CRC cells
inhibited phosphorylation of
mitogen activated protein kinase ( MAPK ) and Akt, which reduced levels of matrix metalloproteinase 2, matrix metalloproteinase 9, and vascular endothelial growth factor ; it also reduced invasiveness of CRC cells, inhibiting signaling via phosphatidylinositol-4,5-bisphosphate 3-kinase, Akt, and MAPK
Yang et al., Hepatology 2013
(Carcinoma, Hepatocellular...) :
Multipathway reporter arrays suggested that
miR-140-5p inhibited transforming growth factor ß ( TGF-ß ) and mitogen activated protein kinase / extracellular signal regulated kinase (
MAPK/ERK ) signaling
Chen et al., Biochem Pharmacol 2013
(Leukemia) :
HQ-induced p38
MAPK and JNK activation were
responsible for suppression of
miR-122 promoter luciferase activity and miR-122 expression ... Activation of p38
MAPK and JNK elicited phosphorylation of c-Jun, ATF-2 and c-Fos, and knock-down of c-Jun, ATF-2 and c-Fos
restored miR-122 expression in HQ-treated cells