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IRS1 — PRKAR1A

Text-mined interactions from Literome

Li et al., Cell Res 2008 : Moreover, activation of PKA induces serine/threonine phosphorylation, reduces tyrosine phosphorylation of insulin receptor substrate 1 (IRS-1) and the association between PKA and IRS-1
Mehebik-Mojaat et al., J Cell Biochem 2009 (Insulin Resistance) : In the presence of leptin and insulin, ( i ) IRS-1 was phosphorylated on Ser ( 307 ) and this effect was prevented by PKA inhibitors, ( ii ) JAK-2 was dephosphorylated, an effect prevented by SHP-1 inhibitor