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PRKAR1A — TNNI3
Text-mined interactions from Literome
Layland et al., J Physiol 2004
(Calcium Signaling) :
PKA dependent phosphorylation of
cardiac troponin I (cTnI) contributes significantly to beta-adrenergic agonist induced acceleration of myocardial relaxation ( lusitropy )
Hinken et al., J Appl Physiol 2006
:
Myocytes ( n = 9 ) from nine Ex pigs had comparable force production but a approximately 30 % increase in peak power output compared with myocytes ( n = 8 ) from eight Sed. Interestingly, Ex myofibrillar samples also had higher baseline
PKA induced phosphorylation levels of
cardiac troponin I , which may contribute to the increase in power
Hanft et al., Am J Physiol Heart Circ Physiol 2009
:
PKA increased the phosphorylation of myosin binding protein C and
cardiac troponin I , as assessed by autoradiography
Kooij et al., J Mol Cell Cardiol 2010
:
Protein kinase A (PKA) mediated phosphorylation of Ser23/24 of
cardiac troponin I (cTnI) causes a reduction in Ca ( 2+ ) -sensitivity of force development
Czuriga et al., Basic Res Cardiol 2012
(Disease Models, Animal...) :
The level of
protein kinase A (PKA) dependent
cardiac troponin I (TnI) phosphorylation was lower in the myocardium surrounding the pacing electrode ( pacing site ) of the failing left ventricle ( LV ) than in the controls
Wattanapermpool et al., J Mol Cell Cardiol 1995
:
Protein kinase A (PKA) dependent phosphorylation of C-protein and
cardiac troponin I (cTnI) is known to be associated with a reduced sensitivity to Ca2+