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MAPK10 — MATK
Text-mined interactions from Literome
Zagozdzon et al., Cell Signal 2006
(MAP Kinase Signaling System) :
Csk homologous kinase (CHK) , unlike Csk,
enhances MAPK activation via Ras mediated signaling in a Src independent manner ... Down-regulation of the expression of endogenous
CHK by RNAi in PC12 cells
led to a significant decrease in
MAPK activation following NGF stimulation
Poehlmann et al., Pathol Res Pract 2010
(Neoplasms) :
Importantly, as current evidence also suggests a role of MAPK 's ( mitogen activated protein kinases ) in cell cycle checkpoint control, we describe in this review both the
ATR/ATM-Chk1/Chk2 signaling pathways as well as the
regulation of cell cycle checkpoints by
MAPK 's as molecular mechanisms in DDR, and how their dysfunction is related to cancer development