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MESP2 — NOTCH3
Text-mined interactions from Literome
Yasuhiko et al., Proc Natl Acad Sci U S A 2006
:
Tbx6 mediated
Notch signaling
controls somite-specific
Mesp2 expression
Yasuhiko et al., Development 2008
:
In cultured cells, Tbx6 binding to the Mesp2 enhancer region is essential for the
activation of
Mesp2 by
Notch signaling
Oginuma et al., Development 2010
:
To explore the establishment of normal Mesp2 expression, we performed computer simulations, which revealed that oscillating
Notch signaling
induces not only the periodic activation of
Mesp2 but also a rostral-caudal gradient of Mesp2 in the absence of striped Notch activity in the anterior PSM
Saga et al., Adv Exp Med Biol 2008
:
Genetic evidence is provided how
Mesp2 regulates
Notch signaling to establish segmental identity in the anterior PSM
Harima et al., Curr Opin Genet Dev 2013
(Anoxia) :
Because of different oscillatory dynamics, oscillation in Fgf signaling dissociates from oscillation in Notch signaling in S-1, a prospective somite region, where
Notch signaling
induces Mesp2 expression when Fgf signaling becomes off