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ANXA1 — CASP3

Text-mined interactions from Literome

Araki et al., Cell Death Differ 2000 : Expression of p35 by infection with AxCANCre resulted in inhibition of caspase-3 activation and resistance to hypoxia induced cell death
Tomioka et al., Brain Res Mol Brain Res 2002 : To examine the role of neuronal caspases in excitotoxic neurodegeneration in vivo, we have generated transgenic mice expressing the baculovirus protein p35 , a potent viral caspase inhibitor , using the neuron-specific calmodulin dependent kinase-II alpha ( CaMKII-alpha ) promoter ... The transgenic expression of p35 consistently inhibited the kainate induced caspase activation, but failed to influence the death of neurons to any extent
Sahdev et al., Biochem Biophys Res Commun 2003 : p35 expression also inhibited cytochrome c release from the mitochondria of oxidant exposed cells and blocked caspase-3 activation
Doloff et al., BMC cancer 2010 (Brain Neoplasms...) : The expression of p35 in Adeno-2B6/p35 infected tumor cells inhibited caspase activation, delaying the death of the CYP2B6 `` factory '' cells that produce active CPA metabolites, and increased bystander tumor cell killing compared to that achieved in the absence of p35
Van de Craen et al., J Mol Biol 1998 : In vitro experiments demonstrated that p35 inhibits caspase-8 directly