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CCND1 — HIF1A
Text-mined interactions from Literome
Ouyang et al., J Cell Physiol 2009
:
Moreover, the soluble nickel induced
cyclin D1 degradation is dependent on its Thr286 residue and
requires IKKalpha, but not
HIF-1alpha , which are both reported to be involved in cyclin D1 down-regulation
Yang et al., Cancer Res 2010
(Breast Neoplasms) :
Here, we show the histone demethylase JMJD2B is regulated by both ERalpha and
HIF-1alpha , drives breast cancer cell proliferation in normoxia and hypoxia, and epigenetically
regulates the expression of cell cycle genes such as
CCND1 , CCNA1, and WEE1