Zhang et al., Free Radic Biol Med 2007
:
Activation of p38 MAPK and HIF-1alpha accumulation were attenuated by N-acetyl-L-cysteine ( antioxidant ), catalase ( hydrogen peroxide scavenger ), or a selective p38 MAPK inhibitor ( SB203580 )
Lin et al., Cell Physiol Biochem 2008
(Brain Ischemia...) :
However, BAPTA-AM ( an intracellular calcium chelator ), SB 203580 ( an inhibitor of p38 ) and HIF-1alpha antisense significantly inhibited the [ Ca ( 2+ ) ] ( i ), p38 MAPK phosphorylation and HIF-1alpha expression respectively