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HIF1A — NOX3

Text-mined interactions from Literome

Haddad et al., Eur Cytokine Netw 2002 : The NADPH-oxidase inhibitor, 4'-hydroxy-3'-methoxy-acetophenone ( HMAP ), which may affect mitochondrial ROS production, attenuated IL-1 beta mediated nuclear translocation and activation of HIF-1 alpha
Yang et al., American journal of physiology. Renal physiology 2003 : NAD ( P ) H oxidase activity may importantly contribute to this posttranscriptional regulation of HIF-1alpha in these cells under physiological conditions
Dong et al., Zhongguo Dang Dai Er Ke Za Zhi 2006 : To study the effect of NADPH oxidase on hypoxia-inducible factor (HIF)-1alpha and endothelin (ET)-1 expression in human umbilical endothelia cells ( HUVECs ) and its possible mechanism ... It is speculated that NADPH oxidase as an oxygen sensor regulates the HIF-1alpha expression by changing the intracellular redox reaction and that except HIF-1, H2O2 might contribute to ET-1 synthesis and release
Oh et al., Neurosci Lett 2008 (Anoxia) : We then showed that LPS induced HIF-1alpha mRNA expression was blocked by an antioxidant, NADPH oxidase inhibitors, and siRNA of gp91phox, a subunit of NADPH oxidase ... Taken together, these results suggest that LPS induces HIF-1alpha mRNA expression and activation via NADPH oxidase and Sp1 in BV2 microglia