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CREB1 — TPO

Text-mined interactions from Literome

Sirotkin et al., J Endocrinol 2004 : A TPO induced increase in expression of PCNA, Bax, PKA, TK, Cdc2/p34 and CREB was observed
Zauli et al., Blood 1998 : Although pharmacological inhibitors of protein kinase C ( chelerytrine and BIM ) and protein kinase A ( H-89 ) failed to block the TPO mediated CREB phosphorylation, a specific inhibitor of the mitogen activated protein kinases ( PD98059 ) completely blocked the ability of TPO to stimulate CREB-PSer133 ... Taken together, these data suggest that CREB plays a role in modulating the expression of genes critical for megakaryocyte differentiation and that the TPO mediated CREB phosphorylation seems to be regulated via mitogen activated protein kinases