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JAK1 — MAPK13

Text-mined interactions from Literome

Takaoka et al., EMBO J 1999 : Protein tyrosine kinase Pyk2 mediates the Jak dependent activation of MAPK and Stat1 in IFN-gamma, but not IFN-alpha, signaling
Wang et al., Oncogene 2000 : PD180970 did not affect MAPK activation by PDGF or the JAK dependent activation of Stat3 by interleukin-6
Krasilnikov et al., Oncogene 2003 (Melanoma) : Tyrosine phosphorylation of STAT3/5 and of JAK2 also increased upon treatment of LU1205 cells with either PD or LY, suggesting that constitutive active MAPK and PI3K signals inhibit tyrosine phosphorylation of JAK/STATs
Shi et al., J Biol Chem 2004 : Although Pyk2 has been implicated in Janus kinase dependent activation of MAPK and Stat1, no role for Pyk2 in the activation of other STAT proteins has been ascribed
Rychli et al., Journal of thrombosis and haemostasis : JTH 2010 : Oncostatin M (OSM) increased Ang2 expression in human umbilical vein endothelial cells via Janus kinase/signal transducer and activator of transcription ( JAK/STAT ) and mitogen activated protein ( MAP ) kinase activation
Pratt et al., J Biol Chem 1996 : Several downstream signaling events induced by GM-CSF stimulation have been described, including activation of tyrosine kinases and tyrosine phosphorylation of cellular proteins ( including beta c ) and activation of the Ras/mitogen activated protein kinase and the JAK/STAT pathways