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CASP10 — RB1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Vrana et al., Oncogene 1999
(Leukemia) :
SAHA mediated apoptosis occurred within the G0G1 and S phase populations, and was associated with decreased mitochondrial membrane potential,
caspase-3 activation , PARP degradation, hypophosphorylation/cleavage of
pRB , and down-regulation of c-Myc, c-Myb, and B-Myb
Cho et al., J Korean Med Sci 2001
:
The levels of MDM2 protein are decreased by a proteasome mediated proteolysis prior to
caspase-3 dependent
pRb and PARP cleavages ... Our results suggest that, in the p53 null status, MDM2 protein level is decreased by proteasome mediated proteolysis prior to
caspase-3 dependent PARP and
pRb cleavages
Wu et al., Mol Biol Rep 2011
(Diabetes Mellitus, Experimental...) :
Ginsenoside
Rb1 reduced infarct size, cardiomyocyte apoptosis and
caspase-3 activity compared to the diabetic group
Hashimoto et al., Evidence-based complementary and alternative medicine : eCAM 2012
:
Rb1 inhibited MPP ( + ) -induced
caspase-3 activation and DNA fragmentation and activated Bcl-xL in MPP ( + ) -treated PC12 cells
Bertin-Ciftci et al., Cell Death Differ 2013
(Breast Neoplasms) :
Moreover,
pRb occupies the noxa promoter together with E2F-1, in a
caspase dependent manner upon ABT-737 treatment
Na et al., Journal of ginseng research 2012
:
In this study, we evaluated the
effects of
G-Rb1 on the mitochondrial permeability transition ( MPT ) and
caspase-3 activity of chondrocyte apoptosis induced by H2O2