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IDDM14 — TNF
Text-mined interactions from Literome
Kulseng et al., Acta Diabetol 1999
(Diabetes Mellitus, Type 1...) :
However, the
role of soluble
TNF receptors in
insulin dependent diabetes mellitus ( type 1 DM ) is not clear
Green et al., Immunol Rev 1999
(Diabetes Mellitus, Type 1...) :
Here we describe a new NOD model for analyzing the
role of
TNF-alpha in
IDDM , TNF-alpha-NOD mice
Picarella et al., J Immunol 1993
(Diabetes Mellitus, Type 1...) :
To understand the
role of
TNF in the regulation of inflammation and the development of autoimmune diseases such as
insulin dependent diabetes mellitus , we produced transgenic mice in which the synthesis of murine TNF-alpha was directed by the rat insulin II promoter
Chosich et al., Autoimmunity 1994
(Diabetes Mellitus, Type 1) :
To investigate a possible
role for
TNF in
IDDM we compared endogenous TNF production in two lines of non-obese diabetic ( NOD ) mice, NOD/Lt and NOD/WEHI, that have a high and low incidence of diabetes, respectively
Winkler et al., Orv Hetil 1998
(Diabetes Mellitus...) :
The present paper summarizes the data ( including the authors ' observations as well ) focusing on the potential
role of
TNF-alpha in the pathogenesis of obesity and
non-insulin dependent diabetes mellitus : alteration of insulin receptor function, lipid metabolism, expression of sulphonylurea receptors, all of them suggested to be related to the TNF-alpha
Nilsson et al., Arterioscler Thromb Vasc Biol 1998
(Diabetes Mellitus, Type 2...) :
The finding of an association between high plasma levels of TNF-alpha and several metabolic abnormalities characteristic for the insulin resistance syndrome suggests that
TNF-alpha may be
involved in the pathogenesis of
non-insulin dependent diabetes mellitus